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1.
Egyptian Journal of Hospital Medicine [The]. 2018; 70 (1): 102-108
in English | IMEMR | ID: emr-190710

ABSTRACT

Background: Glucose-6-Phosphate-Dehydrogenase [G6PD] deficiency is the most common enzyme deficiency globally and is more remarkable in certain parts of the world which had high malaria prevalence in the past. It is an X-linked genetically inherited disorder, where the first presentation can be neonatal jaundice. There are over 300 variants of this disorder based upon the genetics. Although the morbidity and mortality is not very high, the deficiency can be more appropriately managed by proper preventive methods which include screening and avoidance of trigger. Also prompt management of acute hemolysis can save a child from many complications


Methodology: we conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE from January 1987 to March 2017. The following search terms were used: G6PD deficiency, prevalence of G6PD, genetics of G6PD deficiency, management and diagnosis of G6PD


Aim of the work: this study aimed to understand about the etiology, pathophysiology and study various lines of prevention and management of G6PD deficiency in pediatric age group


Conclusion: proper preventive and treatment methods can avoid negative effects on the child's quality of life and reduce morbidity and mortality, therefore the child's care takers must be well informed

2.
Egyptian Journal of Hospital Medicine [The]. 2018; 70 (9): 1464-1467
in English | IMEMR | ID: emr-192678

ABSTRACT

Introduction: Pelvic inflammatory diseases [PID] is caused by infections in the female reproductive tract that includes pelvic peritoneum, ovaries, fallopian tubes, and the endometrium. These infections are commonly caused by Chlamydia trachomatis, Neisseria gonorrhea, or other sexually transmitted infections. 800,000 women get a diagnosis of pelvic inflammatory disease annually in the United States. PID usually causes irreversible damage to the reproductive tract, and treatment mainly depends on preventing further scarring or complications. Immediate broad spectrum antibiotics are indicated. Treatment can include hospitalization as well as surgery


Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, from January 1985 to February 2017. The following search terms were used: pelvic inflammatory diseases, pathogens causing pelvic inflammatory diseases, causes of infertility, treatment and diagnosis of pelvic inflammatory diseases


Aim: In this review, we aim to study the pathophysiology and etiology of pelvic inflammatory diseases, as well as to study the diagnosis, treatment, and possible complications of this condition


Conclusion: It is essential to raise the awareness and knowledge of females in general regarding PID and its symptoms, as early detection will significantly decrease the likelihood of severe complications. Other than infertility, complications of pelvic inflammatory disease include chronic pain. More research is needed in this field to improve management and care of patients suffering from this condition

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